Relation between Elevated Plasma Retinol Binding Protein-4 & Glucose Dysregulation in Type 2 Diabetes
نویسندگان
چکیده
منابع مشابه
Plasma retinol-binding protein-4 concentrations are elevated in human subjects with impaired glucose tolerance and type 2 diabetes.
OBJECTIVE The dysregulation of adipokines is closely associated with the pathogenesis of insulin resistance and type 2 diabetes. Retinol-binding protein-4 (RBP4), a new adipokine, was recently reported to provide a link between obesity and insulin resistance. Here, we examined the relation between plasma RBP4 concentrations and various metabolic parameters in humans. RESEARCH DESIGN AND METHO...
متن کاملRelation of Absolute or Relative Adiposity to Insulin Resistance, Retinol Binding Protein-4, Leptin, and Adiponectin in Type 2 Diabetes
BACKGROUND Central fat mass (CFM) correlates with insulin resistance and increases the risk of type 2 diabetes and cardiovascular complications; however, peripheral fat mass (PFM) is associated with insulin sensitivity. The aim of this study was to investigate the relation of absolute and relative regional adiposity to insulin resistance index and adipokines in type 2 diabetes. METHODS Total ...
متن کاملeffect of omega-3 supplementation on lipocalin 2 and retinol-binding protein 4 in type 2 diabetic patients
background: serum levels of lipocalin 2 (lcn 2) and retinol-binding protein-4 (rbp 4), increase in type 2 diabetes mellitus (t2dm). we sought to determine whether serum lcn 2 and rbp 4 change after an intervention with omega-3 fatty acids supplementation in diabetic patients. methods: forty-five type 2 diabetic patients from iranian diabetic association in tehran, iran in 2013 were randomly rec...
متن کاملEvidence That Kidney Function but Not Type 2 Diabetes Determines Retinol-Binding Protein 4 Serum Levels
OBJECTIVE It has been suggested that retinol-binding protein 4 (RBP4) links adiposity, insulin resistance, and type 2 diabetes. However, circulating RBP4 levels are also affected by kidney function. Therefore, the aim of this study was to test whether RBP4 serum levels are primarily associated with kidney function or type 2 diabetes. RESEARCH DESIGN AND METHODS RBP4 serum concentration was de...
متن کاملElevated plasma retinol-binding protein 4 is associated with increased risk of type 2 diabetes in middle-aged and elderly Chinese adults.
The association between circulating retinol-binding protein 4 (RBP4) and risk of type 2 diabetes has been inconsistent in cross-sectional studies, but prospective evidence is limited. We aimed to investigate whether plasma RBP4 is associated with future development of type 2 diabetes and whether the association could be explained by iron or other risk factors. A total of 2091 Chinese adults age...
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ژورنال
عنوان ژورنال: Islami Bank Medical College Journal
سال: 2013
ISSN: 2408-8552,2225-9171
DOI: 10.3329/ibmcj.v2i1.17312